The protein family-specific amino acid similarity matrices derived from the SUP sub-set of the SABmark database.
Gap INIT/Gap EXT - optimized gap initiation/extension penalties for each family-specific matrix.


The protein family-specific matrices perform significantly better on goups highlighted in GREEN.
The VTML200 matrix performs significantly better on groups highlighetd in RED.
Group N reference alignments Average Length SCOP sunid SCOP description Matrix Gap INIT Gap EXT
1 300 149 46458 Globin-like group1.mat 10 1
2 6 146 46548 alpha-helical ferredoxin group2.mat 19 1
3 10 84 46566 Chaperone J-domain group3.mat 11 2
4 6 80 46589 tRNA-binding arm group4.mat 30 1
5 28 89 46610 "Fe,Mn superoxide dismutase (SOD), N-terminal domain" group5.mat 19 1
6 300 124 46627 monodomain cytochrome c group6.mat 8 1
7 300 68 46689 Homeodomain-like group7.mat 8 1
8 3 85 46771 O6-alkylguanine-DNA alkyltransferase group8.mat 15 5
9 3 112 46775 ARID domain group9.mat 11 1
10 300 111 46785 Winged helix DNA-binding domain group10.mat 9 1
11 15 91 46894 C-terminal effector domain of the bipartite response regulators group11.mat 13 3
12 10 51 46934 UBA-like group12.mat 20 2
13 21 92 46946 S13-like H2TH domain group13.mat 23 1
14 36 77 46955 Putative DNA-binding domain group14.mat 16 1
15 21 115 46966 Spectrin repeat group15.mat 26 2
16 10 144 46978 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain group16.mat 26 2
17 3 56 46997 Bacterial immunoglobulin/albumin-binding domains group17.mat 5 5
18 6 39 47015 Protozoan pheromone proteins group18.mat 15 2
19 3 110 47032 Second domain of FERM group19.mat 10 3
20 3 71 47060 S15/NS1 RNA-binding domain group20.mat 12 2
21 21 80 47097 "HMG1, domains A and B" group21.mat 17 1
22 45 99 47113 Histone-fold group22.mat 17 1
23 21 125 47180 Cytochrome c' group23.mat 10 3
24 3 158 47196 TMV-like viral coat proteins group24.mat 10 2
25 10 166 47203 Acyl-CoA dehydrogenase C-terminal domain-like group25.mat 17 2
26 120 240 47240 Ferritin-like group26.mat 15 4
27 105 147 47305 Interferons/interleukin-10 (IL-10) group27.mat 7 1
28 28 165 47325 Methionyl-tRNA synthetase (MetRS) group28.mat 9 2
29 15 85 47336 ACP-like group29.mat 10 3
30 3 80 47354 Retrovirus capsid protein C-terminal domain group30.mat 18 2
31 3 85 47365 Domain of the SRP/SRP receptor G-proteins group31.mat 7 3
32 6 123 47370 Bromodomain group32.mat 18 1
33 66 70 47413 lambda repressor-like DNA-binding domains group33.mat 8 1
34 21 75 47460 Helix-loop-helix DNA-binding domain group34.mat 17 1
35 300 140 47473 EF-hand group35.mat 11 1
36 21 116 47576 "Calponin-homology domain, CH-domain" group36.mat 20 1
37 10 62 47598 Met repressor-like group37.mat 15 1
38 231 133 47617 "Glutathione S-transferase (GST), C-terminal domain" group38.mat 10 1
39 6 70 47649 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain group39.mat 11 7
40 3 109 47662 t-snare proteins group40.mat 11 10
41 6 88 47699 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin group41.mat 13 1
42 6 86 47729 IHF-like DNA-binding proteins group42.mat 7 2
43 3 89 47742 CO dehydrogenase ISP C-domain like group43.mat 12 1
44 10 75 47773 SAM (sterile alpha motif) domain group44.mat 11 1
45 6 97 47781 RuvA domain 2-like group45.mat 11 3
46 10 114 47815 Flap endonuclease-1 (Fen-1 nuclease) group46.mat 17 1
47 10 110 47836 Retroviral matrix proteins group47.mat 11 1
48 6 79 47863 NKL-like group48.mat 9 1
49 15 282 47875 Annexin group49.mat 19 2
50 3 126 47918 C-terminal domain of alpha and beta subunits of F1 ATP synthase group50.mat 19 1
51 3 141 47944 "Retrovirus capsid protein, N-terminal core domain" group51.mat 11 2
52 91 122 47954 Cyclin-like group52.mat 11 1
53 55 104 47986 DEATH domain group53.mat 9 1
54 3 116 48020 "DNA polymerase III clamp loader subunits, C-terminal domain" group54.mat 14 2
55 3 209 48066 DBL homology domain (DH-domain) group55.mat 18 1
56 10 150 48098 "Regulator of G-protein signalling, RGS" group56.mat 9 1
57 36 346 48114 CCP-like group57.mat 11 1
58 28 196 48150 DNA-glycosylase group58.mat 16 1
59 6 266 48175 C-terminal domain of DNA photolyase group59.mat 20 1
60 36 179 48179 6-phosphogluconate dehydrogenase C-terminal domain-like group60.mat 16 1
61 55 448 48208 Six-hairpin glycosyltransferases group61.mat 8 1
62 10 355 48234 "Hyaluronate lyase-like catalytic, N-terminal domain" group62.mat 19 1
63 10 300 48239 Terpenoid cylases/Protein prenyltransferases group63.mat 8 1
64 15 392 48258 Citrate synthase group64.mat 22 1
65 36 410 48265 Cytochrome P450 group65.mat 12 2
67 3 235 48351 BCR-homology GTPase activation domain (BH-domain) group67.mat 7 2
68 36 246 48371 ARM repeat group68.mat 9 4
69 28 153 48404 Ankyrin repeat group69.mat 32 2
70 28 179 48453 Tetratricopeptide repeat (TPR) group70.mat 14 1
71 3 147 48468 VHS domain group71.mat 11 5
72 28 245 48509 Nuclear receptor ligand-binding domain group72.mat 17 3
73 3 253 48537 Phospholipase C/P1 nuclease group73.mat 32 3
74 10 168 48552 Serum albumin-like group74.mat 16 3
75 6 456 48558 L-aspartase/fumarase group75.mat 46 1
76 45 123 48624 Snake phospholipase A2 group76.mat 17 1
77 171 206 48696 Cytochrome c3-like group77.mat 9 1
78 300 124 48727 V set domains (antibody variable domain-like) group78.mat 10 1
79 300 102 49266 Fibronectin type III group79.mat 5 1
80 3 107 49304 beta-Galactosidase/glucuronidase domain group80.mat 8 1
81 21 107 49309 "Transglutaminase, two C-terminal domains" group81.mat 10 2
82 6 110 49314 Cadherin group82.mat 12 2
83 6 112 49320 Actinoxanthin-like group83.mat 11 1
84 6 150 49341 "Copper chaperone for superoxide dismutase, C-terminal domain" group84.mat 9 3
85 6 130 49348 Clathrin adaptor appendage domain group85.mat 14 3
86 15 95 49373 Invasin/intimin cell-adhesion fragments group86.mat 12 6
87 28 140 49384 Carbohydrate-binding domain group87.mat 8 2
88 21 149 49401 Bacterial adhesins group88.mat 9 1
89 21 192 81315 "Rel/Dorsal transcription factors, DNA-binding domain" group89.mat 10 1
90 6 105 49453 Starch-binding domain group90.mat 22 6
91 3 250 49483 Aromatic compound dioxygenase group91.mat 9 1
92 300 165 49503 Cupredoxins group92.mat 7 1
93 10 136 49575 Synaptotagmin-like (S variant) group93.mat 15 1
94 3 166 49599 TRAF domain-like group94.mat 23 1
95 36 88 49695 gamma-Crystallin-like group95.mat 13 1
96 3 156 49742 PHM/PNGase F group96.mat 6 3
97 10 219 49749 Group II dsDNA viruses VP group97.mat 18 1
98 3 125 49764 HSP20-like chaperones group98.mat 28 1
99 300 165 49785 Galactose-binding domain-like group99.mat 3 1
100 21 223 49820 "Virus capsid protein vp7 (BTV-10 vp7), central (top) domain" group100.mat 21 5
101 6 159 49837 "Adenovirus fiber protein ""knob"" domain" group101.mat 12 3
102 10 143 49843 TNF-like group102.mat 14 1
103 3 104 49864 "Hyaluronate lyase-like, C-terminal domain" group103.mat 23 1
104 6 129 49879 SMAD/FHA domain group104.mat 19 1
105 300 199 49899 Concanavalin A-like lectins/glucanases group105.mat 6 1
106 21 144 50023 Rieske iron-sulfur protein (ISP) group106.mat 16 1
107 3 62 50037 C-terminal domain of transcriptional repressors group107.mat 14 5
108 231 70 50045 SH3-domain group108.mat 15 1
109 10 128 50090 Electron transport accessory proteins group109.mat 22 1
110 15 95 50104 Translation proteins SH3-like domain group110.mat 12 1
111 3 101 50130 GroES group111.mat 23 7
112 120 99 50157 PDZ domain group112.mat 10 1
113 45 72 50183 "Sm motif of small nuclear ribonucleoproteins, SNRNP" group113.mat 12 1
114 66 100 50203 Bacterial enterotoxins group114.mat 11 1
115 6 155 50242 TIMP-like group115.mat 12 1
116 300 145 50249 Nucleic acid-binding proteins group116.mat 5 1
117 3 211 50326 Inorganic pyrophosphatase group117.mat 11 1
118 36 73 50331 MOP-like group118.mat 7 1
119 15 138 50354 Fibroblast growth factors (FGF) group119.mat 12 1
120 28 130 50370 Ricin B-like lectins group120.mat 8 1
121 21 191 50386 STI-like group121.mat 9 2
122 3 116 50405 Actin-crosslinking proteins group122.mat 12 3
123 10 157 50448 Elongation factors group123.mat 17 1
124 3 101 50467 Elongation factor Tu (EF-Tu) group124.mat 21 1
125 10 179 50475 FMN-binding split barrel group125.mat 49 1
126 300 239 50495 Prokaryotic proteases group126.mat 12 1
127 3 76 50616 N-terminal domain of alpha and beta subunits of F1 ATP synthase group127.mat 17 1
128 55 235 50646 Pepsin-like group128.mat 16 1
129 6 182 50678 ValRS/IleRS/LeuRS editing domain group129.mat 22 1
130 36 131 50708 Cdc48 N-terminal domain-like group130.mat 10 1
131 171 118 50729 PH domain-like group131.mat 7 1
132 3 100 50802 Pyruvate kinase (PK) group132.mat 8 4
133 300 151 50814 Lipocalins group133.mat 7 1
134 3 167 50892 Cyclophilin (peptidylprolyl isomerase) group134.mat 9 2
135 6 196 50924 Hemopexin-like domain group135.mat 17 6
136 28 405 50940 Sialidases (neuraminidases) group136.mat 13 1
137 6 311 50978 WD40 repeat-like group137.mat 10 2
138 300 82 51012 "alpha-Amylases, C-terminal beta-sheet domain" group138.mat 5 1
139 10 43 51046 WW domain group139.mat 13 1
140 3 246 51071 Carbonic anhydrase group140.mat 11 1
141 3 209 51098 "delta-Endotoxin (insectocide), middle domain" group141.mat 15 5
142 3 112 51112 Lectin (agglutinin) group142.mat 10 1
143 66 374 51126 Pectin lyase-like group143.mat 5 1
144 28 219 51161 Trimeric LpxA-like enzymes group144.mat 18 1
145 78 190 51182 RmlC-like cupins group145.mat 11 1
146 6 320 51197 Clavaminate synthase-like group146.mat 8 1
147 21 135 51206 cAMP-binding domain-like group147.mat 13 1
148 28 90 51231 Biotinyl/lipoyl-carrier proteins and domains group148.mat 12 3
149 10 79 51247 BC C-terminal domain-like group149.mat 15 3
150 3 154 51262 Glucose permease-like group150.mat 16 2
151 3 119 51280 "Urease, beta-subunit" group151.mat 16 1
152 10 137 51285 Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) group152.mat 13 2
153 3 240 51353 Triosephosphate isomerase group153.mat 10 3
154 66 233 51366 Ribulose-phoshate binding barrel group154.mat 8 1
155 10 345 51396 FMN-linked oxidoreductases group155.mat 12 1
156 10 329 51431 Aldo-keto reductases (NADP) group156.mat 13 1
157 300 445 51445 (Trans)glycosidases group157.mat 10 1
158 28 344 51556 Metallo-dependent hydrolases group158.mat 6 1
159 171 286 51570 Class I aldolase group159.mat 7 1
160 28 256 51604 Enolase C-terminal domain-like group160.mat 10 1
161 15 316 51621 Phosphoenolpyruvate/pyruvate domain group161.mat 10 2
162 3 369 51666 D-xylose isomerase group162.mat 14 7
163 3 298 51679 Bacterial luciferase-like group163.mat 17 1
164 3 265 51695 PLC-like phosphodiesterases group164.mat 20 2
165 6 513 51703 Cobalamin (vitamin B12)-dependent enzymes group165.mat 19 1
166 300 281 51735 NAD(P)-binding Rossmann-fold domains group166.mat 9 1
167 210 131 51905 FAD/NAD(P)-binding domain group167.mat 7 1
168 3 332 51993 Cellobiohydrolase II (Cel6) group168.mat 12 3
170 10 284 52047 RNI-like group170.mat 30 1
171 91 208 52058 L domain-like group171.mat 7 1
172 21 251 52103 Crotonase-like group172.mat 15 1
173 6 94 52113 BRCT domain group173.mat 13 2
174 15 155 52123 Lumazine synthase group174.mat 14 3
175 10 211 52141 DNA glycosylase group175.mat 9 1
176 55 132 52173 CheY-related group176.mat 16 1
177 55 177 52219 Flavodoxin-related group177.mat 10 2
178 6 156 52243 Cobalamin (vitamin B12)-binding domain group178.mat 36 1
179 3 249 52266 SGHN hydrolase group179.mat 9 4
180 3 149 52306 Type II 3-dehydroquinate dehydratase group180.mat 17 6
181 36 202 52317 Class I glutamine amidotransferase-like group181.mat 6 1
182 91 148 52343 "Ferredoxin reductase-like, C-terminal NADP-linked domain" group182.mat 11 1
183 78 256 52374 Nucleotidylyl transferase group183.mat 8 1
184 36 199 81393 "Large, alpha subunit of electron transfer flavoprotein ETFP, N-terminal domain" group184.mat 10 1
185 6 195 52427 DNA photolyase group185.mat 15 2
186 66 111 52440 PreATP-grasp domain group186.mat 11 1
187 66 185 52467 DHS-like NAD/FAD-binding domain group187.mat 8 1
188 10 211 52492 Cell-division protein FtsZ group188.mat 15 3
189 6 211 52499 Cysteine hydrolase group189.mat 26 2
190 136 218 52518 Thiamin diphosphate-binding fold (THDP-binding) group190.mat 7 1
191 300 301 52540 P-loop containing nucleoside triphosphate hydrolases group191.mat 9 1
192 28 317 52743 Subtilisin-like group192.mat 12 1
193 3 326 52768 Arginase/deacetylase group193.mat 7 2
194 15 223 52782 Dihydrolipoamide acetyltransferase group194.mat 18 1
195 3 148 52789 Low-molecular-weight phosphotyrosine protein phosphatases group195.mat 11 1
196 55 219 52799 (Phosphotyrosine protein) phosphatases II group196.mat 14 1
197 3 146 52821 Rhodanese/Cell cycle control phosphatase group197.mat 5 2
198 300 124 52833 Thioredoxin-like group198.mat 5 1
199 15 150 52922 TK C-terminal domain-like group199.mat 14 1
200 3 129 52937 "Pyruvate kinase, C-terminal domain" group200.mat 15 1
201 3 176 52949 Macro domain-like group201.mat 16 1
202 28 111 52955 Anticodon-binding domain of Class II aaRS group202.mat 12 1
203 91 205 52980 Restriction endonuclease-like group203.mat 6 1
204 6 209 53058 beta-carbonic anhydrase group204.mat 18 1
205 153 212 53067 Actin-like ATPase domain group205.mat 5 1
206 55 211 53098 Ribonuclease H-like group206.mat 11 1
207 6 132 53137 Translational machinery components group207.mat 18 1
208 3 260 53169 "Purine nucleoside phosphorylase, PNP" group208.mat 19 6
209 28 312 53187 Zn-dependent exopeptidases group209.mat 11 2
210 78 151 53236 Tetrahydrofolate dehydrogenase/cyclohydrolase group210.mat 12 1
211 15 243 53254 Phosphoglycerate mutase-like group211.mat 21 1
212 55 217 53272 Phosphoribosyltransferases (PRTases) group212.mat 16 1
213 15 200 53301 Integrin A (or I) domain group213.mat 19 1
214 300 271 53335 S-adenosyl-L-methionine-dependent methyltransferases group214.mat 6 1
215 300 407 53383 PLP-dependent transferases group215.mat 6 1
216 28 251 53448 Nucleotide-diphospho-sugar transferases group216.mat 9 2
217 300 360 53474 alpha/beta-Hydrolases group217.mat 6 1
218 21 171 53598 Dihydrofolate reductases group218.mat 14 2
219 3 322 53614 Ribokinase-like group219.mat 8 6
220 3 293 53635 Carbamate kinase group220.mat 14 1
221 3 234 53640 AraD-like aldolase/epimerase group221.mat 14 2
222 3 468 53651 Alkaline phosphatase group222.mat 16 1
223 6 465 53659 Isocitrate/Isopropylmalate dehydrogenases group223.mat 11 1
224 45 161 53676 Ornithine transcarbamoylase group224.mat 13 1
225 6 120 53681 Aspartate/glutamate racemase group225.mat 11 1
226 10 336 53694 1-aminocyclopropane-1-carboxylate deaminase group226.mat 10 1
227 3 455 53702 "Phosphoglucose isomerase, PGI" group227.mat 21 1
228 3 634 53707 "Formate dehydrogenase/DMSO reductase, domains 1-3" group228.mat 18 1
229 15 487 53722 "Aldehyde reductase (dehydrogenase), ALDH" group229.mat 27 1
230 21 141 53738 "Phosphoglucomutase, first 3 domains" group230.mat 13 1
231 3 407 53750 Phosphoglycerate kinase group231.mat 23 2
232 3 499 53756 UDP-Glycosyltransferase/glycogen phosphorylase group232.mat 9 1
233 3 327 53776 Asparaginase type II group233.mat 13 1
234 6 320 53802 Ferrochelatase group234.mat 15 2
235 21 361 53807 Helical backbone metal receptor group235.mat 8 1
236 45 317 53823 L-arabinose binding protein-like group236.mat 9 1
237 153 328 53850 Periplasmic binding protein-like II group237.mat 6 1
238 153 182 53901 Thiolase-like group238.mat 11 1
239 6 144 53927 Cytidine deaminase-like group239.mat 23 2
240 3 103 53933 Microbial ribonucleases group240.mat 8 4
241 55 179 53955 Lysozyme-like group241.mat 8 1
242 190 278 54001 Cysteine proteinases group242.mat 9 1
243 6 159 54060 His-Me finger endonucleases group243.mat 1 1
244 3 127 54077 Ribonuclease A-like group244.mat 9 2
245 66 70 54118 Interleukin 8-like chemokines group245.mat 15 1
246 10 63 54160 Chromo domain-like group246.mat 11 1
247 10 70 54171 DNA-binding domain group247.mat 11 2
248 3 124 54189 Ribosomal proteins L23 and L15e group248.mat 12 1
249 3 153 54197 HIT-like group249.mat 11 2
250 105 140 54211 Ribosomal protein S5 domain 2-like group250.mat 5 1
251 105 90 54236 Ubiquitin-like group251.mat 7 1
252 10 94 54278 CAD domain group252.mat 12 1
253 3 72 54285 MoaD/ThiS group253.mat 10 1
254 171 101 54293 2Fe-2S ferredoxin-related group254.mat 8 1
255 3 116 54328 Staphylokinase/streptokinase group255.mat 8 4
256 28 110 54335 "Superantigen toxins, C-terminal domain" group256.mat 16 1
257 91 119 54373 "FAD-linked reductases, C-terminal domain" group257.mat 7 2
258 10 103 54407 Cystatins group258.mat 20 1
259 28 104 54416 Amine oxidase N-terminal region group259.mat 12 1
260 45 137 54432 Nuclear transport factor-2 (NTF2) group260.mat 10 1
261 105 146 54453 MHC antigen-recognition domain group261.mat 15 2
262 36 149 54497 "Ubiquitin conjugating enzyme, UBC" group262.mat 13 1
263 3 140 54525 Pilin group263.mat 7 3
264 91 120 54535 FKBP immunophilin/proline isomerase group264.mat 13 1
265 21 74 54557 Chitinase insertion domain group265.mat 12 3
266 55 147 54593 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase group266.mat 12 1
267 10 146 54637 Thioesterase/thiol ester dehydrase-isomerase group267.mat 16 3
268 3 65 54655 CI-2 family of serine protease inhibitors group268.mat 9 5
269 6 135 54666 CO dehydrogenase molybdoprotein N-domain-like group269.mat 16 1
270 3 113 54677 "Quinolinic acid phosphoribosyltransferase (NadC), N-terminal domain" group270.mat 11 4
271 15 98 54696 BTB/POZ domain group271.mat 10 2
272 3 123 54713 "Elongation factor Ts (EF-Ts), dimerisation domain" group272.mat 23 1
273 45 114 54720 "Fe,Mn superoxide dismutase (SOD), C-terminal domain" group273.mat 17 1
274 28 89 54768 dsRNA-binding domain-like group274.mat 18 1
275 21 81 54792 Eukaryotic type KH-domain (KH-domain type I) group275.mat 16 1
276 10 88 54815 Prokaryotic type KH domain (KH-domain type II) group276.mat 16 1
277 6 131 54827 Enolase N-terminal domain-like group277.mat 6 2
278 91 107 54862 4Fe-4S ferredoxins group278.mat 9 1
279 15 84 54897 Protease propeptides/inhibitors group279.mat 14 1
280 3 101 54909 Dimeric alpha+beta barrel group280.mat 13 6
281 6 98 54913 GlnB-like group281.mat 23 3
282 6 143 54921 Nucleoside diphosphate kinases group282.mat 20 1
283 231 89 54929 Canonical RBD group283.mat 11 1
284 3 83 54980 EF-G C-terminal domain-like group284.mat 21 2
285 36 72 55009 Metal-binding domain group285.mat 10 1
286 3 90 55021 Regulatory domain in the aminoacid metabolism group286.mat 10 2
287 6 140 55060 "GHMP Kinase, C-terminal domain" group287.mat 14 2
288 3 206 55099 Beta chain group288.mat 5 2
289 6 127 55120 Pseudouridine synthase group289.mat 24 6
290 6 123 55174 Alpha-L RNA-binding motif group290.mat 33 1
291 6 185 55196 "Ribosome recycling factor, RRF" group291.mat 17 1
292 3 124 55241 "Ribulose 1,5-bisphosphate carboxylase-oxygenase" group292.mat 12 1
293 3 78 55288 RPB5 group293.mat 1 1
294 10 127 55298 YjgF-like group294.mat 5 1
295 6 153 55309 Cell-division protein FtsZ group295.mat 20 2
296 3 116 55316 L30e/L7ae ribosomal proteins group296.mat 32 1
297 15 101 55339 MIF-related group297.mat 36 8
298 66 160 55349 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) group298.mat 19 9
299 66 119 55425 "FAD/NAD-linked reductases, dimerisation (C-terminal) domain" group299.mat 9 3
300 3 114 55448 CO dehydrogenase flavoprotein C-terminal domain-like group300.mat 6 3
301 6 148 55464 "Origin of replication-binding domain, RBD-like" group301.mat 8 2
302 6 218 55476 Oxygen-insensitive NAD(P)H nitroreductase group302.mat 14 1
303 231 292 55486 "Metalloproteases (""zincins""), catalytic domain" group303.mat 11 1
304 3 142 55545 beta-N-acetylhexosaminidase-like domain group304.mat 10 2
305 120 116 55551 SH2 domain group305.mat 16 1
306 6 86 55595 HPr-like group306.mat 10 2
307 6 130 55608 Homing endonucleases group307.mat 33 1
308 15 149 55620 Tetrahydrobiopterin biosynthesis enzymes-like group308.mat 15 1
309 28 294 55682 "Class II aminoacyl-tRNA synthetase (aaRS)-like, catalyic domain" group309.mat 15 1
310 66 185 55730 "N-acetyl transferase, NAT" group310.mat 10 1
311 55 129 55762 Cofilin-like group311.mat 12 1
312 3 130 55772 Profilin (actin-binding protein) group312.mat 14 1
313 6 172 55782 GAF domain group313.mat 17 1
314 21 116 55785 PYP-like sensor domain (PAS domain) group314.mat 12 1
315 3 196 55805 IIA domain of mannitol-specific and ntr phosphotransferase EII group315.mat 23 1
316 10 147 55811 Nudix group316.mat 18 1
317 6 275 55832 Thymidylate synthase/dCMP hydroxymethylase group317.mat 19 1
318 3 89 55857 Cytochrome b5 group318.mat 7 1
319 28 187 55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase group319.mat 11 1
320 10 203 55896 Ribonuclease Rh-like group320.mat 8 1
321 10 282 55909 Pentein group321.mat 13 4
322 6 255 55921 Creatinase/aminopeptidase group322.mat 28 1
323 3 303 55931 Glutamine synthase/guanido kinase group323.mat 10 1
324 15 97 55945 TATA-box binding protein-like group324.mat 13 1
325 3 122 55958 "Phosphoglucomutase, C-terminal domain" group325.mat 8 1
326 10 194 55962 Pathogenesis-related protein 10 (PR10)-like group326.mat 12 2
327 3 133 55973 S-adenosylmethionine synthetase group327.mat 14 1
328 45 123 55979 DNA clamp group328.mat 6 1
329 3 633 56004 Molybdemum cofactor-binding domain group329.mat 19 4
330 3 111 56030 Monooxygenase (hydroxylase) regulatory protein group330.mat 11 1
331 6 84 56053 Ribosomal protein L6 group331.mat 14 1
332 45 243 56059 Glutathione synthetase ATP-binding domain-like group332.mat 8 1
333 78 308 88854 "Protein kinases, catalytic subunit" group333.mat 12 1
334 28 210 56177 "FAD-linked oxidases, N-terminal domain" group334.mat 12 1
335 6 116 64419 Holo-(acyl carrier protein) synthase ACPS group335.mat 7 4
336 300 233 56236 Class II glutamine amidotransferases group336.mat 12 1
337 21 243 56281 Metallo-hydrolase/oxidoreductase group337.mat 14 1
338 15 285 56300 Metallo-dependent phosphatases group338.mat 13 1
339 66 171 56328 "Lactate & malate dehydrogenases, C-terminal domain" group339.mat 11 2
340 28 251 56372 Plant cytotoxins group340.mat 14 3
341 28 206 56399 ADP-ribosylation group341.mat 12 1
342 21 132 56426 "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain" group342.mat 10 1
343 276 120 56437 C-type lectin domain group343.mat 7 1
344 3 225 56498 Fibrinogen C-terminal domains group344.mat 11 1
345 3 376 56575 Serpins group345.mat 10 2
346 78 285 56606 "beta-Lactamase, class A" group346.mat 11 1
347 10 508 56635 Heme-linked catalases group347.mat 20 1
348 10 239 56645 Acyl-CoA dehydrogenase NM domain-like group348.mat 15 1
349 10 306 56656 "Inositol monophosphatase/fructose-1,6-bisphosphatase-like" group349.mat 12 3
350 15 447 56672 DNA/RNA polymerases group350.mat 12 1
351 3 315 56753 D-aminoacid aminotransferase-like PLP-dependent enzymes group351.mat 16 1
352 21 220 56784 HAD-like group352.mat 15 2
354 3 223 56838 Colicin group354.mat 12 2
355 3 238 56851 "delta-Endotoxin (insectocide), N-terminal domain" group355.mat 16 1
356 6 180 56855 Bcl-2 inhibitors of programmed cell death group356.mat 23 2
358 3 158 56925 OMPA-like group358.mat 17 8
359 21 446 56935 Porins group359.mat 21 1
360 6 37 57017 Hevein-like agglutinin (lectin) domain group360.mat 28 1
361 210 37 57072 Spider toxins group361.mat 6 1
362 231 48 57097 Scorpion toxin group362.mat 9 1
363 28 110 57185 Growth factor receptor domain group363.mat 13 1
364 6 41 57190 Colipase-like group364.mat 9 1
365 300 47 57196 EGF/Laminin group365.mat 7 1
366 10 50 57262 Leech antihemostatic proteins group366.mat 4 4
367 45 68 57303 Snake venom toxins group367.mat 12 1
368 78 59 57363 Small Kunitz-type ihibitors & BPTI-like toxins group368.mat 8 1
369 78 40 57393 Defensin group369.mat 10 1
370 3 89 57414 Hairpin loop containing domain-like group370.mat 15 9
371 36 43 57424 LDL receptor-like module group371.mat 15 1
372 3 46 57430 Crambin-like group372.mat 7 1
373 66 73 57440 Kringle-like group373.mat 12 1
374 55 53 57467 Ovomucoid/PCI-1 like inhibitors group374.mat 8 1
375 3 57 57493 Trefoil group375.mat 5 1
376 36 113 57501 Cystine-knot cytokines group376.mat 15 1
377 231 64 57535 Complement control module/SCR domain group377.mat 9 1
378 3 53 57553 Blood coagulation inhibitor (disintegrin) group378.mat 1 1
379 10 65 57568 ATI-like group379.mat 13 1
380 36 45 57586 TNF receptor-like group380.mat 16 1
381 15 46 57603 FnI-like domain group381.mat 9 4
382 10 72 57654 HIPIP (high potential iron protein) group382.mat 15 2
383 171 35 57667 C2H2 and C2HC zinc fingers group383.mat 8 2
384 10 45 57702 Zn2/Cys6 DNA-binding domain group384.mat 12 1
385 300 51 57716 Glucocorticoid receptor-like (DNA-binding domain) group385.mat 10 1
386 3 38 57757 Retrovirus zinc finger-like domains group386.mat 10 1
387 3 35 57776 "Microbial and mitochondrial ADK, insert ""zinc finger"" domain" group387.mat 6 1
388 36 62 57783 Zinc beta-ribbon group388.mat 17 1
389 10 58 57802 Rubredoxin-like group389.mat 11 1
390 6 70 57829 Zn-binding ribosomal proteins group390.mat 3 2
391 55 76 57851 "RING finger domain, C3HC4" group391.mat 12 1
392 15 42 57870 Metallothionein group392.mat 20 2
393 6 53 57889 Cysteine-rich domain group393.mat 16 2
394 15 64 57903 FYVE/PHD zinc finger group394.mat 7 4
395 10 108 57925 Inhibitor of apoptosis (IAP) repeat group395.mat 19 1
396 136 139 63381 Ferredoxin reductase FAD-binding domain-like group396.mat 8 1
397 66 212 63411 LuxS/MPP-like metallohydrolase group397.mat 9 1
398 3 49 63451 LEM domain group398.mat 11 3
399 3 84 63571 PABC (PABP) domain group399.mat 6 3
400 6 94 63748 Tudor/PWWP/MBT group400.mat 10 1
401 6 89 88852 SirA-like group401.mat 7 2
402 6 141 75521 Clathrin coat assembly domain group402.mat 7 4
403 3 69 64588 C-terminal domain of ProRS group403.mat 9 1
404 3 44 68907 SAP domain group404.mat 8 1
405 3 225 68925 Phosphoenolpyruvate (PEP) carboxykinase (ATP-oxaloacetate carboxy-liase) group405.mat 15 6
406 3 102 69697 SRP19 group406.mat 14 5
407 28 284 50006 "Hyaluronate lyase-like, central domain" group407.mat 14 2
408 300 121 81296 E set domains group408.mat 3 1
409 6 173 81588 "Poly(A) polymerase N-terminal, catalytic domain" group409.mat 15 1
410 3 175 81319 Bacteriorhodopsin-like group410.mat 9 7
411 6 108 81323 Voltage-gated potassium channels group411.mat 13 5
412 10 149 81373 Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD) group412.mat 20 2
413 3 237 81451 Cytochrome c oxidase subunit III-like group413.mat 38 15
414 6 80 81463 "Cytochrome c oxidase subunit II-like, transmembrane region" group414.mat 19 2
415 3 302 81482 "Bacterial photosystem II reaction centre, L and M subunits" group415.mat 16 5
416 10 127 81623 N-terminal domain of MutM-like DNA repair proteins group416.mat 13 2
417 3 80 82057 Prokaryotic SH3-related domain group417.mat 34 1
418 3 180 82200 Histone lysine methyltransferases group418.mat 30 1
419 300 248 88633 Positive stranded ssRNA viruses group419.mat 10 1
420 21 350 88645 ssDNA viruses group420.mat 8 4
421 3 363 88648 Group I dsDNA viruses group421.mat 11 1
422 3 157 88650 Satellite viruses group422.mat 12 4
423 6 62 88659 Sigma3 and sigma4 domains of RNA polymerase sigma factors group423.mat 11 3
424 3 139 88697 PUA domain-like group424.mat 8 8
425 3 124 88947 Sigma2 domain of RNA polymerase sigma factors group425.mat 19 1
Development of this resource was supported by NIH grant R15GM090228